VITILIGO

OVERVIEW

Vitiligo is an acquired pigmentary disorder of the skin that is characterized by circumscribed, depigmented macules and patches. The condition is frequently associated with disorders of autoimmune origin, with thyroid abnormalities being the most common.

TREATMENT

Nonsurgical treatments

Phototherapy: Induces satisfactory repigmentation in the majority of patients with early or localized disease

Topical corticosteroids and topical calcineurin inhibitors can be used separately or in combination

Laser therapy: Effective on limited, stable patches of vitiligo

Depigmentation therapy: If vitiligo is extensive and attempts at repigmentation have not produced satisfactory results, depigmentation may be attempted in very carefully selected patients

Micropigmentation: Tattooing can be used to repigment depigmented skin in dark-skinned individuals

Surgery

Noncultured epidermal suspensions

Thin dermoepidermal grafts

Suction epidermal grafting

Punch minigrafting

Cultured epidermis with melanocytes or cultured melanocyte suspensions